| ORIGINAL RESEARCH |
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Echocardiography, Natriuretic Peptides, and Risk for Incident Heart Failure in Older Adults: The Cardiovascular Health Study
Objectives: This study sought to examine the potential utility of echocardiography and N-terminal pro–B-type natriuretic peptide (NT-proBNP) for heart failure (HF) risk stratification in concert with ...
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Andreas P. Kalogeropoulos,
Vasiliki V. Georgiopoulou,
Christopher R. deFilippi,
John S. Gottdiener,
Javed Butler,
Cardiovascular Health Study
et al.
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131-140
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| Editorial Comment |
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Echocardiography for the “Superior Doctor” A Call to Action in the Management of Heart Failure⁎
The superior doctor prevents sickness; the mediocre doctor attends to impending sickness; the inferior doctor treats actual sickness. —Extract from 1st Chinese Medical Text. Attributed to Huang Dee Na...
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Walter P. Abhayaratna
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141-143
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Prediction of Coronary Artery Calcium Progression in Individuals With Low Framingham Risk Score: The Multi-Ethnic Study of Atherosclerosis
Objectives: This study sought to determine whether novel markers not involving ionizing radiation could predict coronary artery calcium (CAC) progression in a low-risk population. Background: Increase...
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Tochi M. Okwuosa,
Philip Greenland,
Gregory L. Burke,
John Eng,
Mary Cushman,
Erin D. Michos,
Hongyan Ning,
Donald M. Lloyd-Jones
et al.
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144-153
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A Quantitative Pixel-Wise Measurement of Myocardial Blood Flow by Contrast-Enhanced First-Pass CMR Perfusion Imaging: Microsphere Validation in Dogs and Feasibility Study in Humans
Objectives: The aim of this study was to evaluate fully quantitative myocardial blood flow (MBF) at a pixel level based on contrast-enhanced first-pass cardiac magnetic resonance (CMR) imaging in dogs...
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Li-Yueh Hsu,
Daniel W. Groves,
Anthony H. Aletras,
Peter Kellman,
Andrew E. Arai
et al.
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154-166
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| Editorial Comment |
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Do We Need a New Prescription to View Myocardial Perfusion?⁎
The paper by Hsu et al. () in this issue of iJACC presents the results of a validation study on the use of cardiac magnetic resonance (CMR) imaging to map myocardial blood flow (MBF) at the spatial re...
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Michael Jerosch-Herold,
Otavio R. Coelho-Filho
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167-168
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Impact of Statin Therapy on Plaque Characteristics as Assessed by Serial OCT, Grayscale and Integrated Backscatter–IVUS
Objectives: The purpose of this study was to evaluate the effect of statin treatment on coronary plaque composition and morphology by optical coherence tomography (OCT), grayscale and integrated backs...
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Kousuke Hattori,
Yukio Ozaki,
Tevfik F. Ismail,
Masanori Okumura,
Hiroyuki Naruse,
Shino Kan,
Makoto Ishikawa,
Tomoko Kawai,
Masaya Ohta,
Hideki Kawai,
Tousei Hashimoto,
Yasushi Takagi,
Junichi Ishii,
Patrick W. Serruys,
Jagat Narula
et al.
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169-177
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| Editorial Viewpoint |
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Resolution of Inflammation, Statins, and Plaque Regression⁎
The success of aggressive pharmacological therapy in the prevention and treatment of cardiovascular disease continues to give us renovated energy and constructive hope. Within the last decade, the inc...
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Pedro R. Moreno,
Annapoorna Kini
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178-181
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Determinants and Functional Significance of Myocardial Perfusion Reserve in Severe Aortic Stenosis
Objectives: The purpose of this study was to assess the functional significance of cardiac magnetic resonance (CMR) measures of left ventricular (LV) remodeling and myocardial perfusion reserve (MPR) ...
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Christopher D. Steadman,
Michael Jerosch-Herold,
Benjamin Grundy,
Suzanne Rafelt,
Leong L. Ng,
Iain B. Squire,
Nilesh J. Samani,
Gerry P. McCann
et al.
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182-189
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| Editorial Comment |
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Imaging in Aortic Stenosis—Let the Data Talk⁎
Physiology plays an increasingly clinical role in cardiology. In this issue of iJACC, Steadman et al. () reflect this trend with their report on myocardial perfusion in aortic stenosis (AS) using card...
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K. Lance Gould,
Nils P. Johnson
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190-192
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Is Discordance of Coronary Flow Reserve and Fractional Flow Reserve Due to Methodology or Clinically Relevant Coronary Pathophysiology?
Objectives: The purpose of this study was to determine whether observed discordance between coronary flow reserve (CFR) and fractional flow reserve (FFR) is due to methodology or reflects basic corona...
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Nils P. Johnson,
Richard L. Kirkeeide,
K. Lance Gould
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193-202
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| Editorial Comment |
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FFR and Coronary Flow Reserve: Friends or Foes?⁎
The FAME (Fractional Flow Reserve Versus Angiography for Multivessel Evaluation) study has re-emphasized the importance of assessing functional consequences of coronary stenoses (). In that multicente...
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Heinrich R. Schelbert
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203-206
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| iCONCEPTS |
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Delayed-Enhanced MR Scar Imaging and Intraprocedural Registration Into an Electroanatomical Mapping System in Post-Infarction Patients
Post-infarction arrhythmias are most often confined to scar tissue. Scar can be detected by delayed-enhanced cardiac magnetic resonance. The purpose of this study was to assess the feasibility of pre-...
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Sanjaya Gupta,
Benoit Desjardins,
Timir Baman,
Karl Ilg,
Eric Good,
Thomas Crawford,
Hakan Oral,
Frank Pelosi,
Aman Chugh,
Fred Morady,
Frank Bogun
et al.
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207-210
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| Editorial Comment |
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Integration of CMR Scar Imaging and Electroanatomic Mapping: The Future of VT Ablation?⁎
In this issue of iJACC, Gupta et al. () present their single-center experience with intraprocedural 3-dimensional registration of cardiac magnetic resonance (CMR) scar mapping with voltage maps create...
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Kenneth C. Bilchick
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211-213
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| STATE-OF-THE-ART PAPER |
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Targeted Metabolic Imaging to Improve the Management of Heart Disease
Tracer techniques are powerful methods for assessing rates of biological processes in vivo. A case in point is intermediary metabolism of energy providing substrates, a central feature of every living...
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Moritz Osterholt,
Shiraj Sen,
Vasken Dilsizian,
Heinrich Taegtmeyer
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214-226
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| IMAGING VIGNETTE |
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CMR for the Diagnosis of Right Heart Disease
Right heart disease can present a clinical diagnostic conundrum as a number of pathologies can present with a variety of often nonspecific symptoms. Transthoracic echocardiography (TTE) remains the ma...
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Timothy A. Fairbairn,
Manish Motwani,
John P. Greenwood,
Sven Plein
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227-229
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| LETTERS TO THE EDITOR |
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Mechanism of Asymmetric Leaflet Tethering in Ischemic Mitral Regurgitation: 3D Analysis With Multislice CT
It has been reported that patients with ischemic mitral regurgitation (IMR) caused by inferoposterior myocardial infarction have asymmetric leaflet tethering associated with regional and inferior left...
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Kitae Kim,
Shuichiro Kaji,
Yoshimori An,
Hidetoshi Yoshitani,
Masaaki Takeuchi,
Robert A. Levine,
Yutaka Otsuji,
Yutaka Furukawa
et al.
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230-232
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OCT-Verified Neointimal Hyperplasia Is Increased at Fracture Site in Drug-Eluting Stents
Although drug-eluting stents dramatically reduce stent restenosis, in-stent restenosis still occurs in approximately 10% of sirolimus-eluting stent (SES) implantation cases. Optical coherence tomograp...
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Manabu Kashiwagi,
Atsushi Tanaka,
Hironori Kitabata,
Yasushi Ino,
Hiroto Tsujioka,
Kenichi Komukai,
Yuichi Ozaki,
Kohei Ishibashi,
Takashi Tanimoto,
Shigeho Takarada,
Takashi Kubo,
Kumiko Hirata,
Masato Mizukoshi,
Toshio Imanishi,
Takashi Akasaka
et al.
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232-233
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T2-Weighted CMR: But Where Is Elvis in the End?
A few months ago, in an editorial by Raman et al. (), T2-weighted (T2w) short tau inversion recovery (STIR) imaging, the only validated T2 sequence that was tested against pathology in an experimental...
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Nathan Mewton,
Franck Thuny,
Pierre Croisille
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233-234
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Reply
We thank Dr. Mewton and colleagues for their interest in our paper () and applaud them for raising an important point concerning the validity of current T2-weighted CMR imaging to visualize the area a...
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Matthias G. Friedrich
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234-235
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Reply
We thank Dr. Mewton and colleagues for adding to the discussion regarding T2-weighted cardiac magnetic resonance (CMR). Often, a candid debate will invoke strong reactions, but we are hopeful that rea...
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Han W. Kim,
Raymond J. Kim
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235-236
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| EDITOR'S PAGE |
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CMR-Based Quantitative Myocardial Perfusion: Pixel-Wise and Pound-Wise
Quantitative measurement of myocardial perfusion has been a goal of cardiovascular investigators for a number of years. Positron emission tomography (PET) has allowed assessment of myocardial blood fl...
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Christopher M. Kramer,
Y. Chandrashekhar,
Jagat Narula
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237-238
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